JOINT FUEL

This joint mobility powder drink mix is a multi-ingredient formula designed to support cartilage integrity, everyday comfort, and fluid movement.

Each serving combines:

• Glucosamine Sulphate 1000 mg
• Chondroitin Sulphate 800 mg
• Methylsulfonylmethane (MSM) 3000 mg
• Turmeric Extract (Curcumin) 1000 mg
• Boswellia serrata Extract 600 mg
• Collagen Type II 30 mg
• Hyaluronic Acid 100 mg
• Pterostilbene 50 mg

A synergy of cartilage-building nutrients, connective tissue cofactors, anti-inflammatory botanicals, and antioxidant support.

Recommended use: mix one serving in water, twice daily.

It is recognised for its ability to harmonise key pathways that underlie joint health:promoting matrix synthesis and turnover (glucosamine, chondroitin), supplying sulphur for collagen crosslinking and redox balance (MSM), tempering NFκB/COX2/5LOX inflammatory signalling (curcumin, boswellic acids), and
supporting synovial fluid viscosity and lubrication (hyaluronic acid). Collagen Type II contributes structural building blocks for cartilage, while pterostilbene provides polyphenolbased antioxidant defence that helps protect joint tissues from everyday
oxidative stress. It plays a role in maintaining comfortable range of motion, cushioning and shock absorption, and postactivity recovery; it also supports daytoday resilience by smoothing inflammatory tone and reinforcing the extracellular matrix of cartilage, tendons, and ligaments. Originally it was studied through distinct traditional and modern lenses turmeric and Boswellia in longstanding herbal practice for joint comfort; glucosamine/chondroitin and hyaluronic acid in orthopaedic and sports settings; collagen type II for cartilage support; and pterostilbene as a nextgeneration
antioxidant then brought together to address common barriers to healthy mobility in a single, convenient format.

This drink mix was designed to support daily mobility, joint flexibility, structural resilience, and comfortable activity, but its potential benefits may extend to recovery from physical demand and longterm connectivetissue health. In powdered form (taken twice daily), it is often used for its reported ability to ease stiffness, promote flexible movement, support cartilage and tendon comfort, and sustain active lifestyles while offering easy mixing and a consistent routine.

Not for use during pregnancy or breastfeeding. Consult a qualified clinician if you have medical conditions or take medications.!
This material is informational and not medical advice; the product is not intended to diagnose, treat, cure, or prevent any disease.

Potential Benefits of Joint Fuel:

1. Helps slow structural progression of knee OA (jointspace narrowing): Glucosamine sulphate Longterm RCTs reported reduced jointspace narrowing and symptom improvement over 3 years vs placebo.
2. Reduces cartilage volume loss and bonemarrow lesions: Chondroitin sulphate In a 12month, doubleblind RCT with MRI outcomes, cartilage volume loss
   decreased from 6 months and BMLs improved by 12 months vs placebo.
3. Eases knee pain and improves physical function: MSM (Methylsulfonylmethane). Doubleblind RCTs showed WOMAC pain and function improvements vs placebo within 12 weeks.
4. Reduces osteoarthritis pain with favourable tolerability: Curcumin (turmeric extract). A headtohead multicentre RCT found Curcuma domestica extract
   non-inferior to ibuprofen on WOMAC outcomes (with fewer GI complaints); additional placebocontrolled RCTs confirm kneepain and mobility gains.
5. Improves joint pain and function while modulating inflammatory enzymes: Boswellia serrata (AKBAenriched). Randomized, placebocontrolled trials of
   5Loxin® showed pain and function improvements and reductions in cartilagedegrading markers.
6. Supports comfort and function via cartilagespecific signalling: Undenatured type II collagen (UCII®). In a doubleblind RCT in knee OA, UCII improved
   WOMAC and VAS scores vs placebo (and compared favourably to a glucosamine and chondroitin arm on some measures).
7. Enhances lubrication and reduces symptoms in mild knee OA: Oral hyaluronic acid improved pain and physical function vs placebo. Adds antioxidant
   protection relevant to joint tissues (preclinical
8. Adds antioxidant protection relevant to joint tissues (preclinical): Pterostilbene. In OA models, pterostilbene reduced chondrocyte inflammation/ROS and
   limited cartilage degeneration, supporting an anti-oxidative/anti-inflammatory role.

Scientific Studies Supporting Joint Fuel:
1. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo controlled clinical trial
2. Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double blind, placebo controlled pilot study using MRI
3. Efficacy of Methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial
4. Efficacy and safety of Curcuma Domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multi-centre study:
5. A double blind, randomized controlled study of the efficacy and safety of Boswellia Serrata for treatment of osteoarthritis of the knee
6. Efficacy and tolerability of an undenatured type 2 collagen supplement in modulating knee osteoarthritis symptoms: a multicentre randomized, double blind, placebo-controlled study
7. The effect of oral low molecular weight liquid hyaluronic acid combination with glucosamine and chondroitin on knee osteoarthritis patients with mild knee pain: An 8 week randomized double-blind placebo controlled trial:
8. Pterostilbene inhibits inflammation and ROS production in chondrocytes by activating Nrf2 pathway

!DISCLAIMER: Because this formula influences inflammatory and circulatory pathways, it should be used responsibly: do not combine with anticoagulant/anti-platelet medicines without medical guidance; individuals with shellfish allergy should verify the source of glucosamine. Those with gallbladder issues should use curcumin-containing products cautiously.

Available Flavors: Strawberry Lemonade, Lemon Lime